Delayed administration of high dose human immunoglobulin G enhances recovery after traumatic cervical spinal cord injury by modulation of neuroinflammation and protection of the blood spinal cord barrier
Background/introduction: The neuroinflammatory response plays a major role in the secondary injury cascade after traumatic spinal cord injury (SCI).To date, systemic anti-inflammatory medications such as methylprednisolone sodium succinate (MPSS) have shown promise in SCI.However, systemic immunosuppression can have detrimental side effects.Therefo